CHOLINESTERASE

Intended Use:

Test for quantitative estimation of Cholinesterase activity in human serum and plasma.

Introduction:

There are two forms of cholinesterase; acetyl cholinesterase and cholinesterase which is also commonly referred to as psuedocholinesterase. Acetylcholinesterase is found predominantly in erythrocytes. Cholinesterase is synthesised in the liver and is present in plasma and is the form of the enzyme routinely measured. Cholinesterase is most commonly measured as an indicator of exposure to anticholinesterases (organophosphates, including many insecticides), or inherited abnormal variants of the enzyme, which cause a decreased level of plasma cholinesterase. Increased levels of activity may be present in nephrotic syndrome or in the recovery from liver damage. Clinical diagnosis should not be made on a single test result; it should integrate clinical and other laboratory data.

Features:

  • Method Specific for Cholinesterase
  • Liquid Stable Reagent With Long Shelf Life
  • Fast Result
  • High Linearity

Specification

Methodology Butyrylthiocoline Potassium Hexacynoferrate
Number Of Reagents Two
Sample Volume Required Per Test 15 µL
Linearity 12000 IU/L
Automation Enabled
Pack Sizes 25 ml – 1×20 ml + 1×5 ml
Kit components Reagent bottles
Instructions for Use.
Storage Temperature 2-8 0C
Shelf life 24 months
Kit dimensions 25 ml – 85X105X45 (MM)
Approx. weight of kit 25 ml – 60 gm
Production Capacity 600 mn ml per annum